Translesion DNA synthesis

關於「Translesion DNA synthesis」標籤，搜尋引擎有相關的訊息討論：

Translesion DNA Polymerases - NCBIThis process, termed “translesion DNA synthesis” (TLS), affords the cell additional time to repair the damage before the replicase returns to complete ... tw | twTranslesion DNA Synthesis and Mutagenesis in Eukaryotes - NCBIDirect replication of DNA damage is termed translesion synthesis (TLS), ... Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, Jentsch S 2002.What a difference a decade makes: Insights into translesion DNA ...2007年10月2日 · Yet it was only within the past decade that specialized DNA polymerases for “translesion DNA synthesis” or “TLS” were identified and ...Translesion DNA synthesis in the context of cancer research2011年11月2日 · Specialized DNA polymerases, so called DNA translesion synthesis polymerases (TLS polymerases), can replicate damaged DNA thereby avoiding ...Identification of novel DNA-damage tolerance genes ... - Nature2014年11月25日 · Cells cope with replication-blocking lesions via translesion DNA synthesis (TLS). TLS is carried out by low-fidelity DNA polymerases that ...In vivo evidence for translesion synthesis by the replicative DNA ...2016年5月16日 · Abstract. The intolerance of DNA polymerase δ (Polδ) to incorrect base pairing contributes to its extremely high accuracy during replication ...Characterization of a coupled DNA replication and translesion ...2017年6月26日 · To ensure accurate and faithful DNA synthesis, the DNA replisome must ... conducted using a Superdex 200 10/300 GL column (GE Healthcare ...Regulation of translesion DNA synthesis in mammalian cells - Ma2020年1月25日 · As one important mode of DDT, translesion DNA synthesis (TLS) utilizes multiple low-fidelity DNA polymerases to incorporate nucleotides ...PDIP38/PolDIP2 controls the DNA damage tolerance pathways by ...2019年3月6日 · Stalled replication forks are restored by the DNA damage tolerance (DDT) pathways, error-prone translesion DNA synthesis (TLS) to cope with ...(TLS) to expose replication gaps, a unique cancer vulnerability2021年1月8日 · Introduction: Translesion synthesis (TLS) is a DNA damage tolerance (DDT) mechanism that employs error-prone polymerases to bypass ...